Databases were searched (i.e., PubMed, Scopus, Web of Science, and EBSCO). The search assessed any potential mechanism related to knee pain or injury that could be used in the clinical practice. Our study aimed at assessing, using a systematic search of the most updated evidence, the main factors related to overuse knee-related pain and/or injuries in cyclists. The potential factors associated with overuse injuries and pain in cyclists that are supported by evidence remain unclear.
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